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Rapid mAb Discovery against Cell Surface Receptor Based on B cell Screening on Adherent Cell Lines

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Rapid mAb Discovery against Cell Surface Receptor Based on B cell Screening on Adherent Cell Lines
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Abstract: Advanced high-resolution single B cell screening for rapid antibody discovery using the Beacon platform. Just 29 DAYS from immunization to sequence for a cell surface target.

Covered in this Case Study

  • Goal: delivery of a diverse panel of IgG and scFv anti-Target X binders
  • The partner had previously attempted in vivo discovery in house and suspected the immunogen to be poorly immunogenic
  • Successful antibody discovery campaign against a known poorly-immunogenic cell surface target

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